The Coronavirus Vaccines Will Likely Work. Making Them Fast Will Be Hard.

first_imgThat’s a far cry from the 300 million doses that Operation Warp Speed — the federal effort to accelerate vaccine development — set as a goal this year. It reflects just how difficult and unpredictable the manufacturing process has been. Pfizer, for example, said this summer that it expected to make 100 million doses by year’s end, but has now said it can produce only half that goal.Industry analysts and company executives are optimistic that hundreds of millions of doses will be made by next spring. But the companies — backed with billions of dollars in federal money — will have to overcome hurdles they’ve encountered in the early days of making vaccines. Moderna and Pfizer’s vaccines use new technology that has never been approved for widespread use. They are ramping up into the millions for the first time. Other challenges include promptly securing raw vaccine ingredients and mastering the art of creating consistent, high-quality batches. The promising news that not just one, but two coronavirus vaccines were more than 90 percent effective in early results has buoyed hopes that an end to the coronavirus pandemic is in sight.But even if the vaccines are authorized soon by federal regulators — the companies developing them have said they expect to apply soon — only a sliver of the American public will be able to get one by the end of the year. The two companies, Pfizer and Moderna, have estimated they will have 45 million doses, or enough to vaccinate 22.5 million Americans, by January.- Advertisement –last_img read more

Haiti cholera ‘far worse than expected’, experts fear

first_img Share Sharing is caring! Share The cholera epidemic affecting Haiti looks set to be far worse than officials had thought, experts fear.Rather than affecting a predicted 400,000 people, the diarrhoeal disease could strike nearly twice as many as this, latest estimates suggest. Aid efforts will need ramping up, US researchers told The Lancet journal.The World Health Organization says everything possible is being done to contain the disease and warns that modelling estimates can be inaccurate. Before last year’s devastating earthquake in the Caribbean nation, no cases of cholera had been seen on Haiti for more than a century.The bacterial disease is spread from person-to-person through contaminated food and water. It causes severe diarrhoea and vomiting, and patients, particularly children and the elderly, are vulnerable to dangerous dehydration as a result.Gross underestimateIn the three months between October and December 2010, about 150,000 people in Haiti contracted cholera and about 3,500 died.Around this time, the United Nations projected that the total number infected would likely rise to 400,000. But researchers at the University of California, San Francisco, say this is a gross underestimate.They believe the toll could reach 779,000, with 11,100 deaths by the end of November 2011. Dr Sanjay Basu and colleagues reached their figures using data from Haiti’s ministry of health. They say the UN estimates were “crude” and based on “a simple assumption” that the disease would infect a set portion (2-4%) of Haiti’s 10 million population. Dr Basu’s calculations take into account factors like which water supplies have been contaminated and how much immunity the population has to the disease.They predict the number of cholera cases will be substantially higher than official estimates. “The epidemic is not likely to be short-term,” said Dr Basu. “It is going to be larger than predicted in terms of sheer numbers and will last far longer than the initial projections.” But the researchers say thousands of lives could be saved by provision of clean water, vaccination and expanded access to antibiotics.A spokesman for the World Health Organization said: “We have to be cautious because modelling does not necessarily reflect what’s seen on the ground. “Latest figures show there have been 252,640 cases and 4,672 deaths as of 10 March 2011. “We really need to reconstruct water and sanitation systems for the cholera epidemic to go away completely. “It’s a long-term process and cholera is going to be around for a number of years yet.”By Michelle RobertsHealth reporter, BBC News Tweetcenter_img 43 Views   no discussions HealthLifestyle Haiti cholera ‘far worse than expected’, experts fear by: – March 16, 2011 Sharelast_img read more

Police report two fatal Jennings County crashes in one day

first_imgJennings County, In. — Indiana State Police investigated two fatal crashes in Jennings County on Tuesday.At 8 a.m. a car driven by Sharlene Whitsell, 59, of Seymour, was eastbound on County Road 800 North when she drove into the path of Betty Lou Hicks, 42, of North Vernon, at the intersection of County Road 1300 East. After colliding in the intersection, both cars left the roadway. The Hicks vehicle struck a tree.Hicks was pronounced dead at the scene. Whitsell suffered minor injuries. Investigators say Hicks was not properly restrained.The investigation is ongoing.Around  4:30 p.m. a car driven by Dalton Rinker, 19, of North Vernon, entered State Road 7 from County Road 500 North. Rinker drove into the path of a semi truck driven by Leonel Guillen, 39, of Indianapolis.Rinker was pronounced dead at the scene. Guillen was not injured.The crash remains under investigation.last_img read more

Championship Night is Saturday at Canyon

first_imgBy Rowdy BriggsPEORIA, Ariz. – It has been a long season at Canyon Speedway Park but it all comes down to Championship Night Saturday in the four IMCA divisions that compete regularly at the Arizona speedplant.IMCA Modifieds, IMCA Sunoco Stock Cars, Arizona Differential IMCA Northern SportMods and the IMCA Sunoco Hobby Stocks will be crowning their champions.Admission is $15 for adults. Seniors 60 and over and military are $12 and children 11 and under are free. All-access pit passes can be purchased for $35 for adults while kids ages 7-11 are $20 and 6 years and under are free.All minors under the age of 18 must have a minor release Form filled out and notarized prior to entry into the pits. The form can be found on the track’s www.canyonspeedwaypark.com website.last_img read more

Duke prevails in PASS feature at Port Royal

first_imgKen Duke Jr. won his second Pennsylvania Sprint Series feature in as many 2019 outings Saturday at Port Royal Speedway. (Photo by Christi Baker) Late-charging Johnathan Jones got past Gramley with two laps to go and took second place. Gramley held on for third, followed by Nick Sweigart and Ryan Lynn. The largest field in Central Pennsylvania Sprint Car racing so far this year, 43 cars, entered the race, and 25 of the 26 starters completed the distance. Entries came from as far away as Vermont and North Carolina. It was Duke’s second straight IMCA RaceSaver Sprint Series victory for 2019. PORT ROYAL, Pa. (April 6) – Ken Duke Jr. grabbed the lead from Nathan Gramley in turn two on lap 12 and went on to win Saturday’s 20-lap Pennsylvania Sprint Series feature at Port Royal Speedway.  From his fourth starting position, Duke has quickly assumed the runner-up spot behind Gramley, with Dabrosky, Lynn and Scarborough giving chase. Traffic gave Duke his chance on lap 12 and the 2016 PASS champ made the best of it. At one point his lead stretched to more than three seconds before Jones, who moved from sixth to second over the last five laps, narrowed the final margin.  Feature results – 1. Ken Duke Jr.; 2. Jonathan Jones; 3. Nathan Gramley; 4. Nick Sweigart; 5. Ryan Lynn; 6. Greg Dabrosky; 7. John Scarborough; 8. Zach Newlin; 9. Dave Grube; 10. Cale Riegle; 11. Kyle Ganoe; 12. Drew Ritchey; 13. Robert Garvey; 14. Jaremi Hanson; 15. Jake Waters; 16. Devin Adams; 17. Tim Stallings; 18. Josh Dressley; 19. Scott Lutz; 20. Domenic Melair; 21. Jay Krout; 22. Samantha Lieberman; 23. Scott Ellerman; 24. Dave Wickham; 25. Michael Wenrick; 26. Doug Dodson.last_img read more

Sister Claire Whalen honored as ‘Hoosier Resilience Hero’

first_imgOldenburg, In. — In celebration of Earth Week, Claire Whalen, a Franciscan nun of the Convent of the Sisters of St. Francis in Oldenburg, has been named a Hoosier Resilience Hero by the Environmental Resilience Institute, founded as part of Indiana University’s Prepared for Environmental Change Grand Challenge initiative.While traveling the state as ERI’s assistant director of policy and implementation, Janet McCabe, former acting assistant administrator for air quality with the United States Environmental Protection Agency, has met many Hoosiers dedicated to preparing Indiana for environmental change. The Hoosier Resilience Heroes recognition honors the important contributions of just a few of these residents.“Indiana is full of individuals—in every corner of the state and from every age and walk of life, including government, academia, business, and nonprofits—who are working to make Indiana more resilient in the face of environmental change, and who are making Indiana residents safer and healthier now and for generations to come,” said McCabe. “We are thrilled to recognize these Hoosier Resilience Heroes and lift up their work to inspire us all.”These ten individuals were recognized as Hoosier Resilience Heroes:Shikha Bhattacharya, director and founder, ReTHink, Inc.Jessica Davis, director, IUPUI Office of SustainabilityJohn Gibson, board of directors, Earth Charter IndianaJulia McKenna, senior, John Adams High SchoolIris O’Donnell Bellisario, junior, Purdue UniversityReed Rouch, senior, Brebeuf Jesuit Preparatory SchoolAaron Sawatsky-Kingsley, city forester, City of GoshenJennifer Tank, professor of biological sciences, University of Notre DameLeah Thill, senior environmental planner, Michiana Area Council of GovernmentsSister Claire Whalen, chair, Oldenburg Renewable Energy CommissionSister Whalen has committed a large part of her life to environmental causes. She has a strong desire to help people in her area of the state understand the climate crisis and ways they can work to mitigate the impacts. In her retirement, she chooses to promote sustainable living on our planet Earth, especially in the food and energy sectors.  Known for her work at Michaela Farm and with the Food and Growers Association, Sister Whalen is currently focusing her volunteer efforts on climate change impacts. In 2017 and 2018, she led the Solarize Indiana Southeast initiative, educating residents to install solar; 35 installations were completed at homes and businesses.  In addition, Sister Whalen leads the Oldenburg Renewable Energy Commission to study how their community could move quickly to reduce its carbon footprint in the coming decade. This summer, the Commission will complete a greenhouse gas inventory for the town of Oldenburg, IN, through participation in the Environmental Resilience Institute’s 2019 Resilience Cohort. Furthermore, Sister Whalen regularly advocates for environmental causes to her governmental representatives and encourages others to do the same.“These individuals are making an important difference every day in Indiana,” said Ellen Ketterson, director of the Environmental Resilience Institute.  “In my view, they are true heroes.”Read about all of the 2019 Resilience Heroes on the Environmental Resilience Institute’s website.last_img read more

Louis J. Fasbinder – Brookville

first_imgLouis J. Fasbinder, of Brookville, was born on May 11, 1951 in Batesville, a son to August C. and Sylvia M. Baker Fasbinder.  He was a familiar face around Brookville and Franklin County as the Small Animal Control Officer.  Louis worked for the county for almost 22 years and later spent time at Indian Ridge Golf Course in Oxford.  He was a member of the Sons of the American Legion in Brookville.  Louis loved animals, golfing, and the casinos.  On Thursday, May 21, 2020 at the age of 69, he passed away at the Christ Hospital in Cincinnati.  He was a big hugger and lovingly gave many to his daughter and grandchildren, who will miss him with all their hearts.Those surviving who will cherish Louis’ memory include his daughter, Brandy Todd of Metamora; grandchildren, Gabby and Evan Todd, and Wilder “Bubba” Wesseler; two brothers, Buddy (Kathy) Fasbinder of Florida, and Ron (Peg) Fasbinder of Batesville; a sister, Penny Harrison of Brookville, and several nieces, nephews, aunts, uncles, cousins and many friends.  Besides his parents, he was preceded in death by his son, Dustin T. Fasbinder.In keeping with Louis’ wishes, cremation was chosen and a Celebration of Life will be held at a later date.  Memorial contributions in honor of Louis can be sent directly to the Franklin County Humane Society at 107 High Street, Brookville, Indiana 47012.Please support the family with your memories by going online to www.cookrosenberger.com and signing the guestbook.  The staff of Cook Rosenberger Funeral Home is honored to care for the family of Louis Fasbinder.last_img read more

Pardew: Chelsea’s run will end

first_img Jose Mourinho’s men maintained their unbeaten start to the current campaign by brushing aside Tottenham at Stamford Bridge on Wednesday night. Ahead of Chelsea’s visit to St James’s Park on Saturday, Pardew hailed the quality of Mourinho’s men but said they were bound to slip up sooner or later. Press Association Newcastle boss Alan Pardew believes it will be “impossible” for Chelsea to remain unbeaten in all four major competitions this season.center_img Pardew said: “I think it’s difficult – obviously Arsenal have done it and Chelsea have come pretty close before. “But not in all competitions – that is impossible and I think Jose has admitted that. But they’re making a very good job of it at the moment. “It’s the best Chelsea team that I’ve ever seen and I’ve watched them since I was about 12 so I know them pretty well. I think Jose is pretty pleased with what he’s got.” Pardew is hopeful captain Fabricio Coloccini will be able to make a return on Saturday after missing the best part of a month with a calf problem. Coloccini has been training with his team-mates this week but Pardew must decide whether he is ready for what is likely to prove one of the toughest possible tests. Pardew added: “Coloccini has been on the training ground but whether he’s got enough fitness levels to play a game of this level I don’t know. “I can’t really give a clear message. I’m not trying to hide behind anything but we have had recovery time and I can’t really give a clear indication of how the players are.” last_img read more

Shikhar Dhawan & I share great off the field relationship: Rohit Sharma

first_imgNEW DELHI: Prolific India batsman Rohit Sharma has revealed that he shares a great off the field relationship with his limited-overs opening partner Shikhar Dhawan which ultimately helps them to perform better as a pair on the cricket field. Since catching the eye as an opening pair during India’s victorious 2013 ICC Champions Trophy campaign, Dhawan and Rohit have broken many records together and have been one of India’s most successful opening combinations in white-ball cricket after the legendary pair of Sachin Tendulkar and Sourav Ganguly.”More than anything on the field, we share a great relationship off the field. Knowing each other so well, understanding each other’s comforts and discomforts, that is very important,” said Rohit while speaking with Mayank Agarwal and Dhawan on the series ‘Open Nets with Mayank’ hosted by bcci.tv. “We shared rooms together when we went on India-A tours. So we have got a lot of history together. As a person, we both know each other quite well and that helps a lot on the field.” Dhawan, on his part, admitted the same and hoped they continue to perform for India in the coming years as well. “We clicked on the field from day one and especially after we started opening for India in the 2013 Champions Trophy. However, we shared a good friendship even before that, right from the U-19 days,” said Dhawan “So that comfort reflected during our partnerships on the field. It has been a beautiful journey with him. I have enjoyed it thoroughly and hopefully we can carry it for another few years,” he added. During the course of the conversation, Rohit also talked about his third ODI double hundred which came against Sri Lanka in Mohali in 2017 while Dhawan elaborated on the emotions he felt during his Test debut when he scored a 85-ball hundred against Australia in 2013 at the IS Bindra Stadium. IANS Also watch: #NewsMakers Live: Schools Post Covid in an exclusive chat with Oineetom Ojahlast_img read more

Behind scoring runs, No. 14 Syracuse beats Kansas State in the Cancun Challenge opening round, 70-61

first_imgAs Kayla Goth drained a 3-pointer in the left corner, Tiana Mangakahia calmly jogged to the end line to take the inbounds pass before she slowly walked the ball up the court. The erratic play of the quarter before in the past, Syracuse’s point guard watched as the ball moved cleanly around the arc and to a wide open Digna Strautmane in the corner. With its newfound control, the Orange took charge.No. 14 Syracuse (4-1) recovered from a sloppy third quarter to beat Kansas State (3-1), 70-61, in the first round of the Cancun Challenge. Against the team that hadn’t won in three trips to Cancun and coming off a 10-point win over ranked Texas A&M, the Orange didn’t settle until their erratic play did.Syracuse, who came into the game tied for 233rd in the country with just over 18 turnovers per game, showed no early signs of struggles. A Mangakahia and-1, an Amaya Finklea-Guity lay in and a Strautmane 3-pointer pushed the Orange up ahead nine points late in the first quarter. Scoring runs carried the Orange all game and the Wildcats could only slow down SU’s flashes of brilliance with uncontrolled drives to the rim that drew fouls.K-State showed its defensive prowess with two blocks to end the first half on SU shots down low, but a Mangakahia transition 3 and two-straight Strautmane blocks into a Kiara Lewis bucket in transition put SU in firm control.But then the turnovers hit. Mangakahia coughed the ball up as the buzzer sounded at halftime. When SU’s shots didn’t fall in the third quarter, the turnovers persisted. The Wildcats outscored the Orange 17-6 as fouls, errant passes and three second violations shot SU’s turnover total up to 21 by the end of the period.AdvertisementThis is placeholder textSyracuse’s entry passes were picked, its cross-court passes tracked and its moves telegraphed. Emily Engstler lofted a ball into the left block midway through the third quarter, but Kansas State easily got a hand on it to corral the Wildcat’s second steal of the quarter. The freshman lifted her arms up in frustration. The Orange, who seemingly couldn’t make a mistake early, were making every one.With just over 30 seconds remaining in the quarter Kansas State had led for just 19 seconds of the game, but by the end of third period, the Wildcats reclaimed a lead it hadn’t held since the game’s first bucket.A similar sloppininess started the fourth as Engstler tried another entry pass that was tipped, but she regained control and spun inside for a basket. Then Syracuse started its role. A team that relied on runs got one when it needed. Syracuse started a scoring barrage and never looked back. It slowed its drives, calculated its shots and transferred the pressure to the Wildcats, who lost control of the pace they set in the third. Syracuse didn’t turn the ball over once in the fourth quarter.After playing hero ball in SU’s last game, Mangakahia settled into her late game waltz. The damage was done. Facebook Twitter Google+ Commentscenter_img Published on November 22, 2018 at 4:25 pm Contact Michael: mmcclear@syr.edu | @MikeJMcClearylast_img read more